Published on : October 14, 2024
The effects of hemp extracts on supporting the immune system are becoming increasingly well-known, so it’s no wonder that interest in the cannabidiol found in hemp has been growing in recent years. It is being studied for its potential health benefits, especially in the context of reducing inflammation and supporting the immune system. What are the mechanisms of action, current scientific research, and its potential applications in therapy and supporting immunity?
- Potential mechanisms of CBD’s immune-supporting effects include its anti-inflammatory, immunomodulatory, and antioxidant properties. CBD may regulate the activity of immune cells, such as T and B lymphocytes, and may also affect the secretion of inflammatory cytokines. The time it takes to see a positive effect of CBD on the immune system may vary depending on individual factors, explains Dr. Andrzej Kwaśnica, an expert at Smart Monkey Lab.
1. What is CBD?
Cannabidiol (CBD) is one of over 100 chemical compounds called cannabinoids that occur naturally in the hemp plant (Cannabis sativa). Unlike tetrahydrocannabinol (THC), it does not exhibit psychoactive properties, meaning it does not cause an intoxicating effect. (What’s more, there are studies confirming that CBD actually weakens the effects of THC.) The legality of CBD varies depending on the country and region. In many places around the world, including Poland, CBD isolated from hemp is legal, provided that the THC content does not exceed a certain level (usually 0.2-0.3%).
2. CBD mechanism of action at the cellular level
CBD affects the endocannabinoid system (ECS), which is a complex signaling system present in mammals, including humans. The ECS regulates many physiological processes, such as appetite, sleep, pain, and inflammatory responses. CBD has the ability to interact with the CB1 and CB2 cannabinoid receptors, although it does not bind to them directly. Instead, CBD may affect the activity of these receptors indirectly, modulating the action of endocannabinoids. Additionally, CBD has anti-inflammatory properties by inhibiting the production of pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor (TNF-α). It may also affect the activity of enzymes involved in inflammation, such as cyclooxygenase-2 (COX-2). How long does it take to see the first results?
- Some effects may be visible after a few weeks of regular use, but the full benefits may take a longer period of time to manifest. Be careful and consult your doctor before using different supplements at the same time. There are no direct studies comparing the effectiveness of different forms of CBD (oil, capsules, tinctures) in strengthening immunity. Further clinical studies are needed in this area, explains Dr. Andrzej Kwaśnica, an expert at Smart Monkey Lab.
3. Scientific Research on CBD and Inflammation
Many preclinical and clinical studies suggest that CBD oil has beneficial effects on various infections and inflammations. Here are some examples:
- Animal studies have shown that CBD can alleviate symptoms of rheumatoid arthritis by inhibiting the production of pro-inflammatory cytokines and reducing joint swelling.
- In clinical trials on patients with Crohn’s disease (inflammatory bowel disease), CBD has shown potential to relieve inflammatory symptoms and improve quality of life.
- There is evidence that CBD may be helpful in treating multiple sclerosis (MS), an autoimmune disease characterized by inflammation and damage to nerve tissue.
While the results are promising, further large-scale clinical trials are needed to fully evaluate the effectiveness and safety of CBD in treating inflammation.
4. The effect of CBD on the immune system
The immune system plays a key role in regulating inflammatory processes in the body. Research suggests that CBD may affect immune function in several ways:
- CBD may modulate the activity of immune system cells such as T and B lymphocytes, macrophages and dendritic cells, which may impact the body’s immune response.
- CBD has immunomodulatory properties, meaning it can both inhibit and stimulate the immune response depending on the circumstances.
- There are reports that CBD may support tissue regeneration by regulating inflammatory processes and stimulating stem cell proliferation.
However, it should be remembered that the effect of CBD on the immune system is complex and depends on many factors, such as the dose, duration of use, and the health of the person taking CBD.
5. Practical use of CBD
CBD is available in various forms, such as oil, capsules, creams, and gels. The form you choose depends on your personal preferences and the purpose of use. There are no clear-cut recommendations for CBD dosage, as it can vary based on individual factors such as body weight, age, and health. It is generally recommended to start with a low dose and gradually increase it until you achieve the desired effect. It is also important to consult a doctor before starting CBD, especially if you are taking other medications or dietary supplements, as interactions may occur.
6. The Future of CBD Research
While the research to date has shown promising results, many aspects of CBD’s effects still require further investigation. Key areas for future research include:
- better understanding of CBD’s mechanisms of action at the molecular and cellular level,
- Conduct more large-scale clinical trials to assess the efficacy and safety of CBD in treating various inflammatory and autoimmune conditions
- research on optimal dosage and forms of administration of CBD for various therapeutic indications,
- exploration of potential synergies between CBD and other plant compounds or conventional medicines.
Despite the promising prospects, there are also challenges and barriers to CBD research, such as differences in legal regulations in different countries and difficulties in standardizing and quality control of CBD products.
Summary
Scientific studies suggest that CBD oil may have a beneficial effect on reducing inflammation and strengthening our immunity. However, it is important to remember that many aspects of CBD’s effects still require further research and verification. Before starting to use CBD as a supplement or therapy, it is recommended to consult a doctor, especially if you are taking other medications or supplements. It is also important to choose cannabinoid products from trusted sources and follow dosage recommendations. Although CBD seems to be a promising therapeutic option, it should not be considered a miracle cure for all ailments. The key is to take a balanced approach and treat CBD as a potential complement, not a substitute for conventional medical care. Are you interested in this article? Do you want to know how CBD can help? See how Smart Monkey Lab products from the REGENERATION line can help you.